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How do NK cells and Tc cells kill invading foreign cells?


A) by engulfing and devouring them
B) by inhibiting protein synthesis in the foreign cells
C) by digesting their nuclear material
D) by punching holes in their membranes

E) B) and C)
F) A) and B)

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Which of the following statements is true of innate immunity?


A) It only includes physical barriers.
B) It is highly pathogen specific.
C) Both of these statements are true.
D) Neither of these statements is true.

E) A) and D)
F) A) and C)

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Which of the following are the first cells in the blood that encounter an antigen?


A) B cells
B) Dendritic cells
C) Macrophages
D) T cells

E) None of the above
F) C) and D)

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Which of the following statements is true of the structure of immunoglobulins?


A) Each immunoglobulin molecule is made of two polypeptide chains.
B) Each immunoglobulin molecule is made of four different polypeptide chains.
C) Each immunoglobulin molecule is made of four identical polypeptide chains.
D) Each immunoglobulin molecule is made of two identical light chains and two identical heavy chains.

E) B) and D)
F) B) and C)

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Which portion of a T-cell receptor binds to an antigen?


A) the constant region
B) the variable region
C) neither the constant region nor the variable region
D) both the constant region and the variable region

E) C) and D)
F) B) and D)

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How do plasma cells respond to antigens in the blood?


A) They directly attack the antigens.
B) They secrete soluble antibodies in the blood.
C) Both of these are responses of plasma cells.
D) Neither of these is a response of plasma cells.

E) B) and C)
F) B) and D)

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Which of the following molecules that are on the surface of HIV strongly bind to CD4 molecules?


A) gp41
B) p24 capsid
C) gp120
D) p17 matrix

E) A) and B)
F) None of the above

Correct Answer

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Identify a difference between T-cell receptors and other immunoglobulins.


A) Unlike other immunoglobulins, T-cell receptors do not have constant and variable regions.
B) Unlike other immunoglobulins, T-cell receptors respond to nucleic acid antigens.
C) Unlike other immunoglobulins, T-cell receptors cannot undergo somatic mutations.
D) Unlike other immunoglobulins, T-cell receptors are antigen specific.

E) All of the above
F) A) and D)

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Which of the following is not a side effect of glucocorticoids?


A) Diabetes
B) Osteoporosis
C) Skin atrophy
D) None, these are all side effects of glucocorticoids.

E) None of the above
F) A) and D)

Correct Answer

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What is the smallest unit of an antigen that is capable of binding with an antibody?


A) MHC class I
B) An epitope
C) A paratope
D) MHC class II

E) A) and B)
F) A) and D)

Correct Answer

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In which part of a phagocyte are antigens destroyed?


A) in the mitochondria
B) in the cytoplasm
C) in the lysosomes
D) inside the nucleus

E) A) and B)
F) None of the above

Correct Answer

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Which of the following can be antigens?


A) nucleic acids
B) polysaccharides
C) proteins
D) all of these

E) A) and D)
F) A) and B)

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Which class of immunoglobulins has the lowest concentration in the serum?


A) IgA
B) IgD
C) IgE
D) IgM

E) B) and C)
F) A) and D)

Correct Answer

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Which of the following cells target and perforate the surfaces of abnormal cells?


A) B cells
B) Macrophages
C) NK cells
D) T cells

E) All of the above
F) B) and D)

Correct Answer

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Which of the following immune cells develop into plasma cells?


A) B cells
B) Helper T cells
C) Macrophages
D) Memory T cells

E) All of the above
F) None of the above

Correct Answer

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What does "CD" stand for in the name of the molecule CD3?


A) cell destroyer
B) cluster determinant
C) cluster disperser
D) compact dimer

E) All of the above
F) None of the above

Correct Answer

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Which of the following is not a lymphoid organ?


A) the spleen
B) the thymus
C) the thyroid
D) the tonsils

E) A) and B)
F) A) and C)

Correct Answer

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Which type of biomolecules are antibodies made of?


A) glycoproteins
B) lipoproteins
C) glycerophospholipids
D) sphingolipids

E) B) and C)
F) All of the above

Correct Answer

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Which of the following cells release perforins to target abnormal cells?


A) B cells
B) Macrophages
C) NK cells
D) TH cells

E) A) and C)
F) B) and C)

Correct Answer

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Which of the following is true of antigens?


A) They elicit an immune response.
B) They have a molecular weight of less than 3000.
C) They have a simple structure.
D) They are polypeptide chains, which have only one amino acid.

E) B) and C)
F) A) and C)

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